Recently, the journal Stem Cells Transl Med published a clarification to the previously published article “Hydrogel and amniotic membrane powder accelerate wound healing…” based on the results of research by scientists from Northern California (USA) Sean V Murphy et al. Recall that the amniotic membrane is obtained from the placenta, and we previously reported on the achievements of Ukrainian scientists in the direction of clinical use of such drugs.
This is a method of treatment of gunshot and mine-explosive wounds using the amniotic membrane developed by the Institute of Cell Therapy (more at the link https://cryobank.ua/uk/news-uk/platsenta-dlya-likuvannya-j-reabilitatsiyi-poranenyh/and experience of the use of the amniotic membrane in ophthalmic operations (more at the link https://csict.com.ua/rnd-research-articles/efficiency-of-the-cryopreserved-allogeneic-amniotic-membrane-transplantation-in-patients-with-infectious-and-neurotrophic-keratitis/?lang=uk). A Ukrainian soldier was treated with the amniotic membrane preparation produced by the Cryobank of the Institute of Cell Therapy (more at the link лінком https://cryobank.ua/uk/news-uk/ukrayinskyh-voyiniv-likuyut-iz-vykorystannyam-tkanynnyh-preparativ-platsenty-vygotovlenyh-ikt/
Interest in the use of placenta preparations in the treatment of wounds is observed worldwide. After all, the placenta is a source of stem cells and valuable biologically active substances, among them pro-angiogenic growth factors, that is, those that promote the development of new blood vessels. This is very important in the regeneration of damaged tissues, wound healing processes.
Research by American scientists mentioned above demonstrated that hydrogel and powder from the amniotic membrane accelerate wound healing, in part due to the processes of epithelization. This was confirmed by the results of histological studies, which noted the formation of a mature epidermis (surface layer of the skin) and the skin itself of the same structure as healthy areas. Preparations of the amniotic membrane in the treatment of wounds were characterized by higher efficiency than other medicinal products, especially in preventing the development of contractures. Histologically, the epidermis when using other wound-healing agents was thinner than in the case of treatment with placenta preparations.
In Ukraine, it is possible to preserve the placenta, as well as umbilical cord blood and umbilical cord collected during childbirth, in the first state-licensed Cryobank of the Institute of Cell Therapy.
Source: https://pubmed.ncbi.nlm.nih.gov/31328435/, https://pubmed.ncbi.nlm.nih.gov/39126708/
