Container of the future– already today
Collection of the umbilical cord blood, umbilical cord and placenta is the first step to the “universal drugs” – stem cells and other preparations obtained from the most valuable biological material. This biological material is collected in the maternity clinic, directly in the delivery room after the baby is born.
- But what happens to the biological material (the most frequently it is the umbilical cord blood and placenta) next?
- How and where is it packed?
- How is it transported? How important are the conditions of transportation?
- Aren’t the valuable cells damaged during their transportation to the laboratory?
- And how is the approach to transportation changed with the use of our “container of the future” – developed and certified specially for the transportation of the biological material?
Important conditions for the proper transportation
1. Sterile containers for different materials.
All biological material should get immediately to the special sterile containers.
Sterility is the easiest item to follow, this requirement is met by any modern containers for collecting umbilical cord blood and other biomaterials. However, the “container of the future” used in the collection of biological material for further processing and storage in the Institute of Cell Therapy Cryobank has advantages even in this simplest aspect.
- Our kit contains a sterile 250 ml capacity for the umbilical cord blood, supplied with an anticoagulant. We will tell about it below
- Our kit is packaged with five vials for the maternal peripheral blood, every of which also contains anticoagulant
- Our kit also includes a special container for the umbilical cord tissue. The latter contains a sterile salt solution with the antibiotic allowing to preserve the umbilical cord tissue during transportation. As all containers in our kit, the capacity for the umbilical cord storage is resistant to the pressure changes and provides sterility of the tissue till the moment of its delivery to the laboratory
2. Anticoagulant that does not affect the quality of the biological material.
The container, in which obstetrician-gynecologist collects the umbilical cord blood after child birth already contains an anticoagulant, a compound preventing blood clotting and allows to deliver the biological material to the laboratory in unchanged condition.
Most cord blood banks use heparin as anticoagulant. However, it is already known that it negatively affects the quality of obtained stem cells.
FDA, the Food and Drug Administration does not recommend to use heparin as anticoagulant at transportation of blood, from which in future stem cells will be obtained. In these cases FDA recommends to use citrate-phosphate-dextrose (CPD), a compound which before everything else does not have any negative influence on the stem cells quality and allows to obtain 50% more stem cells compared to blood that was transportated in the containers with heparin.
In our “container of the future” only citrate-phosphate-dextrose (CPD), an anticoagulant recommended by FDA is used.
3. Temperature regimen.
Alteration of the temperature regimen at transportation of the cord blood and other biological material obtained at birth to the laboratory may cause the loss of cell viability and decrease the stem cells functions. Collected cord blood should be transported at temperature in the range of 4-30°С. However, the transportation of blood at a temperature close to the upper limit is also not recommended – the results of blood tests for some infectious diseases will be invalid due to storage at temperatures above 25°C during the day.
The kit we provide is in a thermal container that provides protection against temperature changes several tens of times longer than other standard kits currently used by the cord blood banks.
4. Protection from damage.
The obtained biological materials are usually transported in a car. Given the peculiarities of Ukrainian roads, it is important that in our “container of the future” all containers are securely fastened and will not roll over, fall, hit or get deformed during transportation
Uniqueconstructionofthecontainer – guaranteeofstemcellsprotection
To ensure temperature support, our certified containers for the transport of biological materials from which stem cells will be derived use state-of-the-art gel bags with phase change material (PCM).
The peculiarity of this new material is that it does not require cooling or freezing, but instead absorbs or emits heat to maintain the desired temperature. Due to this, in a kit with containers in which umbilical cord blood, maternal blood, umbilical cord and placenta are collected, a moderate temperature is constantly maintained, necessary to maintain the high quality of all biological materials. All of them get to the laboratory in a condition that allows to perform a maximum of tests, select all the necessary fractions, get the maximum possible number of stem cells of the highest quality.
Vacuum panels, which make up the walls of the container help to maintain the desired temperature. They provide thermal insulation 10 times more efficiently than materials applied for conventional thermal containers used by other umbilical cord blood banks.
Temperature control is carried out automatically – a special built-in indicator constantly monitors the temperature during the transportation of biological material and reports that it may approach the lower or upper limit of the norm during transportation.
Simplicity + effectiveness + environmental friendliness: a step to the future
It is not for nothing that we call our containers for transporting umbilical cord blood “containers of the future”. We took care of everything. The containers in the kit guarantee the highest quality of the obtained stem cells. All measures to maintain the temperature work perfectly. But we took care not only of this.
The entire set of containers, the entire system, including gel bags and insulation panels, is a compact and aesthetic portfolio with a concise design, created from materials that can be almost completely recycled or reused (as insulation panels).
We deliberately went on to make our umbilical cord blood collection container as environmentally friendly as possible. After all, caring for the future of those whose stem cells we will preserve today is also caring for the environment that we will leave to those who were born now.