It has been known since the 1970s that umbilical cord blood is a rich source of stem cells, primarily hematopoietic, what allows it to be used for more than 30 years instead of bone marrow in the treatment of leukemia. However, as scientists have shown, hematopoietic stem cells are not only able to replace the altered hematopoiesis, they secrete numerous biologically active substances that have a restorative, immunomodulatory, anti-inflammatory effect. These are the properties of stem cells that determine their increasing use in cardiology, neurology, pulmonology, hepatology, orthopedics and traumatology.
Over the past decade, various neurological centers around the world have developed treatments for cerebral palsy and autism using umbilical cord blood stem cells. In particular, the Marcus Center for Cell Therapy and the Duke Center for Autism and Brain Development (USA) conducted a clinical study led by renowned industry experts Dr. Joan Kurtsberg and Geraldine Dawson, in which children with autism were infused umbilical cord blood. The researchers studied the effect of the latter on the symptoms of autism in young patients.
In the first such clinical study, 25 children aged 2-6 years with autism were treated, 70% of whom showed clinical improvement due to one or more symptoms of the disease. This clinical improvement correlated with electroencephalography and magnetic resonance imaging. Therefore, Duke University has planned the next clinical trial to evaluate the effectiveness of umbilical cord blood in the treatment of autism, the results of which have already been published in the Journal of Pediatrics.
This study treated 180 children with autism, aged 2-7 years. The study was randomized, double-blind, placebo-controlled, and prospective.
All children were treated with stem cells of their own or donor umbilical cord blood on an outpatient basis. The dose of stem cells was 25 million cells per kg of body weight.
Analyzing the effectiveness of umbilical cord blood in the treatment of autism, doctors noted that umbilical cord blood had a positive effect not on all studied indices but in children aged 4-7 years it was found that cell therapy improved communication skills, better eye tracking and positive changes in electroencephalogram. .
July 22 is the World Brain Day. On this day, numerous medical forums are being held worldwide, where experts discuss current issues of neurology and neurosurgery, as well as raise public awareness of methods for the prevention of brain diseases, the possibility of their diagnosis and treatment. Cell therapy is one of the most innovative and promising methods of treating neurological diseases. You can learn more about the possibilities of treating neurological diseases with stem cells in Ukraine on the website of the clinic of the Institute of Cell Therapy https://www.stemcellclinic.com/therapy/reabilitatsiya-pislya-insultu-i-nevrologichnih-zahvoryuvan/